Arimoclomol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Arimoclomol 是热休克蛋白 (HSP) 的共同诱导剂，可用于治疗肌萎缩侧索硬化症 (ALS) 的研究。

Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).(In Vivo):In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased.

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Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis. Animal Model:Male Wistar rats weighing 240 to 270 gDosage:20 mg/kg Administration:Administered intragastrically, for 5 daysResult:Had a protective effect against CCK-induced acute pancreatitis.

BRX-220 free base

Cytoskeleton/Cell Adhesion Molecules

HSP

AP-1| LOX| NF-κB| Parasite

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289893-25-0

313.78

C14H20ClN3O3

>98% (HPLC)

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O[C@@H](CO\N=C(/Cl)c1cccn(=O)c1)CN1CCCCC1

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(-20℃)

With Ice Pack

≥ 2 years