Anguizole ( Anguizole )

产品货号. M14509 CAS No. 442666-98-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Anguizole
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2).
产品描述

Anguizole is a HCV NS4B inhibitor targeting second amphipathic helix of NS4B (NS4B-AH2), blocks genotype 1b HCV replication with EC50 of 310 nM; disrupts NS4B-AH2-mediated biological functions of NS4B, NS4B's dimerization/multimerization, its proper subcellular localization, as well as its interaction with NS5A.
同义词

Anguizole
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

Infection
适应症

——

CAS Number

442666-98-0
分子量

408.81
分子式

C17H11ClF2N4O2S
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

O=C(C1=NN2C(C(F)(Cl)F)=CC(C3=CC=CO3)=NC2=C1)NCC4=CC=CS4
化学全称

Pyrazolo[1,5-a]pyrimidine-2-carboxamide, 7-(chlorodifluoromethyl)-5-(2-furanyl)-N-(2-thienylmethyl)-

1. Choi M, et al. Virus Genes. 2013 Dec;47(3):395-407.

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产品手册

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