Aloperine ( Aloperine )

产品货号. M18812 CAS No. 56293-29-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Aloperine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Aloperine 具有抗炎、抗菌、抗病毒和抗肿瘤特性。
产品描述

Aloperine is an alkaloid with diverse biological activities including antiviral, anticancer, antioxidant, and anti-inflammatory actions. It inhibits HIV-1 replication and envelope-mediated cell-cell fusion in vitro. Aloperine also inhibits the growth of HL-60, U937, and K562 leukemia cell lines.
体外实验

Aloperine (1-20 μM; 24 hours) gives growth-inhibitory IC50 values in cancer cells ranges from 0.04 to 1.36 mM, the IC50 values in HL-60, U937, K562, EC109, A549 and HepG2 cells are 0.04, 0.27, 0.36, 1.11, 1.18 and 1.36 mM,respectively.Aloperine (1-20 μM; 24 hours) induces apoptosis and decreases bcl-2 expression in HL-60 cells.Aloperine (20–100 μM; 18 hours) induces autophagy and formation of acidic vacuole in HL-60 cells.
体内实验

——
同义词

Aloperine
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

56293-29-9
分子量

232.36
分子式

C15H24N2
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 5.56 mg/mL (23.93 mM)
SMILES

C1CCN2C[C@H]3C[C@@H]([C@H]2C1)C=C1[C@H]3NCCC1
化学全称

(6R,6aR,13R,13aS)-1,3,4,6,6a,7,8,9,10,12,13,13a-dodecahydro-2H-6,13-methanodipyrido[1,2-a:3',2'-e]azocine

1. Yuan XY, et al. Eur J Pharmacol, 2010, 629(1-3), 147-152.

计算器

产品手册

关联产品

Lappaol A

Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents.
Vanatone

它是通过离子交换和亲和层析从恶臭假单胞菌 JD1 中纯化的芳基酮单加氧酶的底物。
Adrenocorticotropic ...

Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist.Peptide fragments of ACTH (1-39) were formed during in vitro incubation of the peptide with membrane preparations. ACTH (1-39) were isolated by high pressure liquid chromatography, and peptide fragments of ACTH (1-39) characterized by determination of amino acid composition and NH2- terminal residue.