
Acifluorfen
CAS No. 50594-66-6
Acifluorfen ( —— )
产品货号. M28315 CAS No. 50594-66-6
三氟羧草醚是一种原卟啉原氧化酶 (PROTOX) 抑制剂除草剂,可促进原卟啉 IX (PPIX) 的积累,并诱发啮齿动物肝脏肿瘤。三氟羧草醚对敏感植物物种的色素和脂质产生强烈的光氧化破坏。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥332 | 有现货 |
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100MG | ¥494 | 有现货 |
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200MG | ¥721 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Acifluorfen
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述三氟羧草醚是一种原卟啉原氧化酶 (PROTOX) 抑制剂除草剂,可促进原卟啉 IX (PPIX) 的积累,并诱发啮齿动物肝脏肿瘤。三氟羧草醚对敏感植物物种的色素和脂质产生强烈的光氧化破坏。
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产品描述Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species.(In Vitro):The effect of Acifluorfen on glutathione and ascorbate levels in cucumber (Cucumis sativus L.) cotyledon discs is investigated to assess the relationship between herbicide activity and endogenous antioxidants. Acifluorfen decreases the levels of glutathione and ascorbate over 50% in discs exposed to less than 1.5 hours of white light (450 microeinsteins per square meter per second). Acifluorfen also causes the rapid depletion of ascorbate in far-red light grown plants which are photosynthetically incompetent. (In Vivo):Dietary treatment with 2500 ppm Acifluorfen for up to 13 weeks increases Cyp2b10 expression in the livers of wild-type mice, but not in CAR-knockout (CARKO) mice. Microscopically, Acifluorfen treatment-induces cytotoxic changes, including hepatocellular necrosis and inflammation, and causes regenerative changes accompanied by prolonged increases in the numbers of proliferating cell nuclear antigen-positive hepatocytes in WT mice .
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体外实验The effect of Acifluorfen on glutathione and ascorbate levels in cucumber (Cucumis sativus L.) cotyledon discs is investigated to assess the relationship between herbicide activity and endogenous antioxidants. Acifluorfen decreases the levels of glutathione and ascorbate over 50% in discs exposed to less than 1.5 hours of white light (450 microeinsteins per square meter per second). Acifluorfen also causes the rapid depletion of ascorbate in far-red light grown plants which are photosynthetically incompetent.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Dyrk1A|Dyrk1B
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研究领域——
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适应症——
化学信息
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CAS Number50594-66-6
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分子量361.66
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分子式C14H7ClF3NO5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 25 mg/mL (69.13 mM)
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SMILESOC(=O)c1cc(Oc2ccc(cc2Cl)C(F)(F)F)ccc1[N+]([O-])=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ogawa Y, et al. Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Nat Commun. 2010 Oct 5;1:86.
产品手册




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