Acetylcysteine
CAS No. 616-91-1
Acetylcysteine ( Acetylcysteine; NSC 111180; NAC )
产品货号. M15331 CAS No. 616-91-1
Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom.
纯度: >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥476 | 有现货 |
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25MG | ¥864 | 有现货 |
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50MG | ¥1526 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Acetylcysteine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom.
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产品描述Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom. This compound is sold as a dietary supplement commonly claiming antioxidant and liver protecting effects.Acetylcysteine (also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC) is primarily used as a mucolytic agent and in the management of acetaminophen poisoning. It is a derivative of cysteine with an acetyl group attached to the amino group of cysteine. NAC is essentially a prodrug that is converted to cysteine (in the intestine by the enzyme aminoacylase 1) and absorbed in the intestine into the blood stream. Cysteine is a key constituent to glutathione and hence administration of acetylcysteine replenishes glutathione stores. Acetylcysteine can also be used as a general antioxidant which can help mitigate symptoms for a variety of diseases exacerbated by reactive oxygen species (ROS). For instance, acetylcysteine is commonly used in individuals with renal impairment to prevent the precipitation of acute renal failure. Acetylcysteine has been shown to have efficacy in treating mild to moderate traumatic brain injury including ischemic brain injury, particularly in reducing neuronal losses, and also reducing cognitive and neurological symptoms when administered promptly after injury. N-acetylcysteine is now widely used in the treatment of HIV, and it has reported efficacy in chronic obstructive pulmonary disease and contrast-induced nephropathy. Acetylcysteine is also being successfully used to treat a variety of neuropsychiatric and neurodegenerative disorders including cocaine, cannabis, and smoking addictions, Alzheimer’s and Parkinson’s diseases, autism, compulsive and grooming disorders, schizophrenia, depression, and bipolar disorder. Recent data also shows that N-acetylcysteine inhibits muscle fatigue and can be used to enhance performance in endurance events and in exercise and endurance training.
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同义词Acetylcysteine; NSC 111180; NAC
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通路Endocrinology/Hormones
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靶点ATPase
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受体ACY1; GluR; NF-κB; NAPQI
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number616-91-1
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分子量163.19
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分子式C5H9NO3S
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纯度>98%(HPLC)
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溶解度Ethanol: 33 mg/mL (202.21 mM); Water: 33 mg/mL (202.21 mM); DMSO: 33 mg/mL (202.21 mM)
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SMILESSC[C@@H](C(O)=O)NC(C)=O
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化学全称Cysteine, N-acetyl-, L-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Alvirez-Freites EJ, et al. Antimicrob Agents ChemOthers, 2002, 46(4), 1022-1025.
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