AVN-322 ( AVN322 )

产品货号. M10684 CAS No. 1194574-68-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

AVN-322
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
产品描述

A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia; significantly restores both scopolamine- and MK-801-induced cognitive dysfunction and demonstrates antipsychotic potential.Alzheimer Disease Phase 2 Clinical
同义词

AVN322
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

Neurological Disease
适应症

Alzheimer Disease

CAS Number

1194574-68-9
分子量

393.89
分子式

C17H20ClN5O2S
纯度

>98% (HPLC)
溶解度

——
SMILES

O=S(C1=C2N=CC(CN(C)CC3)=C3N2N=C1NC)(C4=CC=CC=C4)=O.[H]Cl
化学全称

N,7-dimethyl-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-2-amine hydrochloride

1. Ivachtchenko AV, et al. Curr Alzheimer Res. 2017;14(3):268-294.

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