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AU-1235
CAS No. 1338780-86-1
AU-1235 ( AU1235 )
产品货号. M11362 CAS No. 1338780-86-1
AU-1235 是一种新型、特异性分枝杆菌膜蛋白大 3 (MmpL3) 抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥794 | 有现货 |
|
| 5MG | ￥1604 | 有现货 |
|
| 10MG | ￥2495 | 有现货 |
|
| 25MG | ￥4204 | 有现货 |
|
| 50MG | ￥6099 | 有现货 |
|
| 100MG | ￥8586 | 有现货 |
|
| 500MG | ￥17172 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AU-1235
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述AU-1235 是一种新型、特异性分枝杆菌膜蛋白大 3 (MmpL3) 抑制剂。
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产品描述AU-1235 is a novel, specific mycobacterial membrane protein large 3 (MmpL3) inhibitor with MIC of 0.1 ug/mL (0.3 uM) against Mtb H37Rv.
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体外实验AU1235 is similarly active against MDR isolates of M. tb displaying resistance to isoniazid, rifampicin, and pyrazinamide in addition to streptomycin, fluoroquinolones and/or ethambutol. AU1235 also inhibits Mycobacterium smegmatis and Mycobacterium fortuitum although the MICs (3.2 to 6.4 μg/ml) are significantly higher than against M. tb and M. bovis BCG.
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体内实验——
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同义词AU1235
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number1338780-86-1
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分子量324.347
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分子式C17H19F3N2O
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纯度>98% (HPLC)
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溶解度DMSO : 6 mg/mL 18.50 mM
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SMILESC1C2CC3CC1CC(C2)(C3)NC(=O)NC4=C(C(=C(C=C4)F)F)F
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化学全称N-Tricyclo[3.3.1.13,7]dec-1-yl-N'-(2,3,4-trifluorophenyl)urea
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Grzegorzewicz AE, et al. Nat Chem Biol. 2012 Feb 19;8(4):334-41.
2. Stanley SA, et al. ACS Chem Biol. 2012 Aug 17;7(8):1377-84.
