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AN-2728
CAS No. 906673-24-3
AN-2728 ( Crisaborole;AN2728;AN 2728 )
产品货号. M16514 CAS No. 906673-24-3
A potent PDE4 inhibitor with IC50 of 0.49 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥308 | 有现货 |
|
| 50MG | ￥405 | 有现货 |
|
| 100MG | ￥672 | 有现货 |
|
| 200MG | ￥899 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AN-2728
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent PDE4 inhibitor with IC50 of 0.49 uM.
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产品描述A potent PDE4 inhibitor with IC50 of 0.49 uM; also shows inhibition against PDE1A3, PDE3Cat, and PDE7A1; suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines.Dermatitis Phase 2 Clinical
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同义词Crisaborole;AN2728;AN 2728
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通路Angiogenesis
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靶点PDE
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受体PDE4
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研究领域Inflammation/Immunology
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适应症Dermatitis
化学信息
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CAS Number906673-24-3
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分子量251.05
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分子式C14H10BNO3
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 32 mg/mL
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SMILESN#CC1=CC=C(OC2=CC=C3C(B(O)OC3)=C2)C=C1
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化学全称Benzonitrile, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Akama T, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2129-32.
2. Nazarian R, et al. Curr Opin Investig Drugs. 2009 Nov;10(11):1236-42.
3. Freund YR, et al. FEBS Lett. 2012 Sep 21;586(19):3410-4.
2. Nazarian R, et al. Curr Opin Investig Drugs. 2009 Nov;10(11):1236-42.
3. Freund YR, et al. FEBS Lett. 2012 Sep 21;586(19):3410-4.
产品手册
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