AFN-1252 ( API-1252;Debio-1452 )

产品货号. M15347 CAS No. 620175-39-5

A potent inhibitor of bacterial enoyl-ACP reductase FabI.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥478	有现货
5MG	￥786	有现货
10MG	￥1256	有现货
25MG	￥2341	有现货
50MG	￥3588	有现货
100MG	￥5289	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

AFN-1252
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent inhibitor of bacterial enoyl-ACP reductase FabI.
产品描述

A potent inhibitor of bacterial enoyl-ACP reductase FabI; demonstrates MICs of 0.015 and 0.008 ug/ml for S. aureus ATCC 29213 and S. aureus ATCC 33592 (MRSA), respectively; demonstrates a Staphylococcus-specific spectrum of activity.Bacterial Infection Phase 2 Clinical
同义词

API-1252;Debio-1452
通路

GPCR/G Protein
靶点

Antibacterial
受体

enoyl-acylcarrierproteinreductase(FabI)
研究领域

Infection
适应症

Bacterial Infection

化学信息

CAS Number

620175-39-5
分子量

375.42
分子式

C22H21N3O3
纯度

>98% (HPLC)
溶解度

DMSO: 5.8 mg/mL (Need ultrasonic)
SMILES

O=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O
化学全称

2-Propenamide, N-methyl-N-[(3-methyl-2-benzofuranyl)methyl]-3-(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-3-yl)-, (2E)-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Karlowsky JA, et al. Antimicrob Agents Chemother. 2007 Apr;51(4):1580-1.
2. Karlowsky JA, et al. Antimicrob Agents Chemother. 2009 Aug;53(8):3544-8.
3. Parsons JB, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15378-83.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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