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AFN-1252
CAS No. 620175-39-5
AFN-1252 ( API-1252;Debio-1452 )
产品货号. M15347 CAS No. 620175-39-5
A potent inhibitor of bacterial enoyl-ACP reductase FabI.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥478 | 有现货 |
|
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1256 | 有现货 |
|
| 25MG | ￥2341 | 有现货 |
|
| 50MG | ￥3588 | 有现货 |
|
| 100MG | ￥5289 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AFN-1252
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent inhibitor of bacterial enoyl-ACP reductase FabI.
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产品描述A potent inhibitor of bacterial enoyl-ACP reductase FabI; demonstrates MICs of 0.015 and 0.008 ug/ml for S. aureus ATCC 29213 and S. aureus ATCC 33592 (MRSA), respectively; demonstrates a Staphylococcus-specific spectrum of activity.Bacterial Infection Phase 2 Clinical
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同义词API-1252;Debio-1452
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通路GPCR/G Protein
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靶点Antibacterial
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受体enoyl-acylcarrierproteinreductase(FabI)
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number620175-39-5
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分子量375.42
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分子式C22H21N3O3
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纯度>98% (HPLC)
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溶解度DMSO: 5.8 mg/mL (Need ultrasonic)
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SMILESO=C(N(C)CC1=C(C)C2=CC=CC=C2O1)/C=C/C3=CC(CC4)=C(N=C3)NC4=O
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化学全称2-Propenamide, N-methyl-N-[(3-methyl-2-benzofuranyl)methyl]-3-(5,6,7,8-tetrahydro-7-oxo-1,8-naphthyridin-3-yl)-, (2E)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Karlowsky JA, et al. Antimicrob Agents Chemother. 2007 Apr;51(4):1580-1.
2. Karlowsky JA, et al. Antimicrob Agents Chemother. 2009 Aug;53(8):3544-8.
3. Parsons JB, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15378-83.
2. Karlowsky JA, et al. Antimicrob Agents Chemother. 2009 Aug;53(8):3544-8.
3. Parsons JB, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15378-83.
产品手册
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