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ACT-389949
CAS No. 1258417-54-7
ACT-389949 ( —— )
产品货号. M23429 CAS No. 1258417-54-7
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2795 | 有现货 |
|
| 10MG | ￥3969 | 有现货 |
|
| 25MG | ￥6367 | 有现货 |
|
| 50MG | ￥8829 | 有现货 |
|
| 100MG | ￥11988 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ACT-389949
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes.
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产品描述ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. It has the potential for the treatment of inflammatory disorders.
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同义词——
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通路Others
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靶点Other Targets
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受体FPR2/ALX
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研究领域——
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适应症——
化学信息
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CAS Number1258417-54-7
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分子量428.4
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分子式C20H18F2N6O3
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纯度>98% (HPLC)
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溶解度DMSO:10 mg/mL (23.34 mM; ultrasonic and adjust pH to 1 with HCl)
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SMILESO=C(NC1=NN(N=C1)CC2=NC(C(F)(C)F)=CO2)C3=C(OC(C)=N3)C4=CC=CC(C)=C4
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Stalder AK,et al. Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949. Br J Clin Pharmacol. 2017 Mar;83(3):476-486.
产品手册
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