7-O-Methylrosmanol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

7-O-甲基迷迭香醇可以有效抑制 FSK 诱导的 CRE、PEPCK-C 和 G6Pase 基因启动子控制下的荧光素酶表达，这可能有助于其降血糖活性。

7-O-Methylrosmanol can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity.In order to find new effective HIV protease inhibitors, two diterpenes (carnosic acid and carnosol) were isolated from rosemary (Rosmarinus officinalis L.), and rosmanol and semisynthetic derivatives (7-O-Methylrosmanol, 7-O-ethylrosmanol, and 11,12-O,O-dimethylcarnosol) were prepared. The inhibitory activity of all six compounds against HIV-1 protease was tested. The carnosic acid showed the strongest inhibitory effect (IC90 = 0.08 micrograms/ml). The same compound was also assayed against HIV-1 virus replication (IC90 = 0.32 micrograms/ml).

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GPCR/G Protein

cAMP

cAMP

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113085-62-4

360.45

C21H28O5

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (277.44 mM)

[H][C@@]12[C@@H]3OC(=O)[C@@]1(CCCC2(C)C)c1c(O)c(O)c(cc1[C@@H]3OC)C(C)C

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(-20℃)

With Ice Pack

≥ 2 years