021-51111890/在线客服
购物车（）
sales@molnova.cn
  • 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
    963389683
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号
首页- Products - Immunology/Inflammation - ROS - 5-Hydroxyoxindole

5-Hydroxyoxindole

CAS No. 3416-18-0

5-Hydroxyoxindole ( —— )

产品货号. M28142 CAS No. 3416-18-0

5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ￥340 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
拼团 产品询价 大包装询价 加入购物车

生物学信息

  • 产品名称
    5-Hydroxyoxindole
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria.
  • 产品描述
    5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria . 5-Hydroxyoxindole has lipid peroxidation inhibition activity and free radical DPPH scavenging.(In Vitro):5-Hydroxyoxindole was less potent MAO-A inhibitor (IC50 56.8 microM) than isatin (31.8 microM) and especially 5-hydroxyisatin (6.5 microM), but it was the only highly selective MAO-A inhibitor among the all compounds studied (IC50 MAO-A:IC50 MAO-B = 0.044) . (In Vivo):In blood plasma, 5-hydroxyoxindole levels were quite stable . The maximal 5-hydroxyoxindole concentration in plasma was: 5.4 nM (5-hydroxyoxindole molecular weight: 149) .
  • 同义词
    ——
  • 通路
    Immunology/Inflammation
  • 靶点
    ROS
  • 受体
    serotonin;Norepinephrine;Dopamine
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    3416-18-0
  • 分子量
    149.1
  • 分子式
    C8H7NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Oc1ccc2NC(=O)Cc2c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Shao L, et al. Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1438-41.
计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册
关联产品

  • Febuxostat

    Febuxostat is a Xanthine Oxidase Inhibitor. The mechanism of action of febuxostat is as a Xanthine Oxidase Inhibitor.

  • Allopurinol

    Allopurinol (Zyloprim) is axanthine oxidaseinhibitor with anIC50of 7.82±0.12 μM.

  • Blumeatin

    Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.

登录 注册