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5-Hydroxyoxindole
CAS No. 3416-18-0
5-Hydroxyoxindole ( —— )
产品货号. M28142 CAS No. 3416-18-0
5-Hydroxyoxindole 已被确定为吲哚的尿代谢物，它是通过肠道细菌的色氨酸酶活性从色氨酸产生的。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥340 | 有现货 |
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| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称5-Hydroxyoxindole
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述5-Hydroxyoxindole 已被确定为吲哚的尿代谢物，它是通过肠道细菌的色氨酸酶活性从色氨酸产生的。
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产品描述5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria . 5-Hydroxyoxindole has lipid peroxidation inhibition activity and free radical DPPH scavenging.(In Vitro):5-Hydroxyoxindole was less potent MAO-A inhibitor (IC50 56.8 microM) than isatin (31.8 microM) and especially 5-hydroxyisatin (6.5 microM), but it was the only highly selective MAO-A inhibitor among the all compounds studied (IC50 MAO-A:IC50 MAO-B = 0.044) . (In Vivo):In blood plasma, 5-hydroxyoxindole levels were quite stable . The maximal 5-hydroxyoxindole concentration in plasma was: 5.4 nM (5-hydroxyoxindole molecular weight: 149) .
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体外实验——
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体内实验——
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同义词——
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通路Immunology/Inflammation
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靶点ROS
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受体serotonin|Norepinephrine|Dopamine
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研究领域——
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适应症——
化学信息
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CAS Number3416-18-0
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分子量149.149
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分子式C8H7NO2
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纯度>98% (HPLC)
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溶解度——
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SMILESOc1ccc2NC(=O)Cc2c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shao L, et al. Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1438-41.
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