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4-Hydroxytamoxifen
CAS No. 68392-35-8
4-Hydroxytamoxifen ( Afimoxifene )
产品货号. M15614 CAS No. 68392-35-8
A selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1045 | 有现货 |
|
| 50MG | ￥1725 | 有现货 |
|
| 100MG | ￥2657 | 有现货 |
|
| 200MG | ￥3993 | 有现货 |
|
| 500MG | ￥6391 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称4-Hydroxytamoxifen
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen.
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产品描述A selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen; exhibits more potent estrogen agonist/antagonist activity and can inhibit MCF-7 and MDA-MB-231 cell proliferation with IC50 values of 27 and 18 uM, respectively.Breast Cancer Phase 2 Clinical
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同义词Afimoxifene
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体Others
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研究领域Cancer
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适应症Breast Cancer
化学信息
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CAS Number68392-35-8
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分子量387.51
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分子式C26H29NO2
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纯度>98% (HPLC)
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溶解度DMSO: 71 mg/mL (183.2 mM); Ethanol: <1 mg/mL; Water: <1 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESOC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)/CC)C=C1
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化学全称(Z)-4-(1-(4-(2-aminoethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Mansel R, et al. Breast Cancer Res Treat. 2007 Dec;106(3):389-97.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Seeger H, et al. Horm Metab Res. 2004 May;36(5):277-80.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Seeger H, et al. Horm Metab Res. 2004 May;36(5):277-80.
产品手册
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