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4-Butylresorcinol
CAS No. 18979-61-8
4-Butylresorcinol ( Butylresorcinol )
产品货号. M20556 CAS No. 18979-61-8
4-Butylresorcinol 是一种有效的酪氨酸酶抑制剂 (IC50 : 11.27 μM)，在化妆品中用作脱色剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥381 | 有现货 |
|
| 100MG | ￥583 | 有现货 |
|
| 500MG | ￥1426 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称4-Butylresorcinol
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述4-Butylresorcinol 是一种有效的酪氨酸酶抑制剂 (IC50 : 11.27 μM)，在化妆品中用作脱色剂。
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产品描述4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM) and is used in cosmetics as a depigmenting agent.
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体外实验It shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression.4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression.
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体内实验——
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同义词Butylresorcinol
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通路Proteasome/Ubiquitin
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靶点Tyrosinase
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受体Tyrosinase
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研究领域——
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适应症——
化学信息
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CAS Number18979-61-8
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分子量166.22
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分子式C10H14O2
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纯度>98% (HPLC)
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溶解度DMSO:150 mg/mL (902.42 mM)
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SMILESCCCCc1ccc(O)cc1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kim D S Kim S Y Park S H et al. Inhibitory Effects of 4-n-Butylresorcinol on Tyrosinase Activity and Melanin Synthesis[J]. Biological & Pharmaceutical Bulletin 2005 28(12):2216-2219.
产品手册
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