1-Methylxanthine ( —— )

产品货号. M26013 CAS No. 6136-37-4

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HNMR

HPLC

MSDS

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产品名称

1-Methylxanthine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP).
产品描述

1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.(In Vitro):1-Methylxanthine exhibits similar activities to other naturally occurring methylxanthines. Unlike caffeine and theobromine, 3-Methylxanthine, and 1-methylxanthine do not occur naturally at high levels in plants. 1-Methylxanthine (3 mM; for 30 min) increases the radiation-induced clonogenic and apoptotic cell (RKO human colorectal cancer cells carrying wild type protein 53 kDa (p53)) death.
同义词

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通路

Proteasome/Ubiquitin
靶点

Endogenous Metabolite
受体

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研究领域

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适应症

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1.Marks KR, et al. Synthesis and evaluation of 1-cyclopropyl-2-thioalkyl-8-methoxy fluoroquinolones.Bioorg Med Chem Lett. 2011 Aug 1;21(15):4585-8.

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