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(S,R,S)-AHPC-C10-NH2

CAS No. 2341796-74-3

(S,R,S)-AHPC-C10-NH2 ( VH032-C10-NH2 )

产品货号. M26943 CAS No. 2341796-74-3

(S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥786 有现货
10MG ¥1158 有现货
25MG ¥1912 有现货
50MG ¥2811 有现货
100MG ¥4188 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    (S,R,S)-AHPC-C10-NH2
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    (S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.
  • 产品描述
    (S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • 同义词
    VH032-C10-NH2
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    RGS19; RGS4
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2341796-74-3
  • 分子量
    613.9
  • 分子式
    C33H51N5O4S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Levi L. Blazer et al.Reversible, Allosteric Small-Molecule Inhibitors of Regulator of G Protein Signaling Proteins. Molecular Pharmacology September 2010 vol.78 no.3 524-533
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