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(S,R,S)-AHPC-C10-NH2
CAS No. 2341796-74-3
(S,R,S)-AHPC-C10-NH2 ( VH032-C10-NH2 )
产品货号. M26943 CAS No. 2341796-74-3
(S,R,S)-AHPC-C10-NH2 是一种合成的 E3 连接酶配体-接头缀合物，包含基于 (S,R,S)-AHPC 的 VHL 配体和用于 BET 靶向 PROTAC 的接头。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥786 | 有现货 |
|
| 10MG | ￥1158 | 有现货 |
|
| 25MG | ￥1912 | 有现货 |
|
| 50MG | ￥2811 | 有现货 |
|
| 100MG | ￥4188 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称(S,R,S)-AHPC-C10-NH2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述(S,R,S)-AHPC-C10-NH2 是一种合成的 E3 连接酶配体-接头缀合物，包含基于 (S,R,S)-AHPC 的 VHL 配体和用于 BET 靶向 PROTAC 的接头。
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产品描述(S,R,S)-AHPC-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词VH032-C10-NH2
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通路Others
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靶点Other Targets
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受体RGS19| RGS4
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研究领域——
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适应症——
化学信息
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CAS Number2341796-74-3
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分子量613.86
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分子式C33H51N5O4S
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCCCN)C(C)(C)C)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Levi L. Blazer et al.Reversible, Allosteric Small-Molecule Inhibitors of Regulator of G Protein Signaling Proteins. Molecular Pharmacology September 2010 vol.78 no.3 524-533
产品手册
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