021-51111890
购物车（）
sales@molnova.cn
(Rac)-AMG8379
CAS No. 1641574-26-6
(Rac)-AMG8379 ( (Rac)-AMG8380 )
产品货号. M26409 CAS No. 1641574-26-6
(Rac)-AMG8379 是 AMG8379 的外消旋体。 AMG8379 是一种有效的、口服活性的、选择性的磺酰胺 NaV1.7 拮抗剂（hNaV1.7 和 mNaV1.7，IC50 分别为 8.5 和 18.6 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2373 | 有现货 |
|
| 5MG | ￥3629 | 有现货 |
|
| 10MG | ￥5330 | 有现货 |
|
| 25MG | ￥7995 | 有现货 |
|
| 50MG | ￥11178 | 有现货 |
|
| 100MG | ￥15309 | 有现货 |
|
| 500MG | ￥30618 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称(Rac)-AMG8379
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述(Rac)-AMG8379 是 AMG8379 的外消旋体。 AMG8379 是一种有效的、口服活性的、选择性的磺酰胺 NaV1.7 拮抗剂（hNaV1.7 和 mNaV1.7，IC50 分别为 8.5 和 18.6 nM）。
-
产品描述(Rac)-AMG8379 is a racemate of AMG8379. AMG8379 is a potent, orally active and selective sulfonamide NaV1.7 antagonist(hNaV1.7 and mNaV1.7 with IC50s of 8.5 and 18.6 nM , respectively ).
-
体外实验——
-
体内实验——
-
同义词(Rac)-AMG8380
-
通路Others
-
靶点Other Targets
-
受体ATF4| ATF6| ERK| GRP78| MMP
-
研究领域——
-
适应症——
化学信息
-
CAS Number1641574-26-6
-
分子量543.93
-
分子式C25H16ClF2N3O5S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=S(NC1=NOC=C1)(C2=CC(C=CC(N3C4=CC(F)=C(C=C4OC)C5=CC(Cl)=CC(F)=C5)=O)=C3C=C2)=O.[Racemate]
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Zhang B, Han H, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.
产品手册
关联产品
-
Eupatoriochromene
Eupatoriochromene retard seed germination , reduced radicle and hypocotyl growth of weed and crop plant seedlings and increased adventitious root formation of mung bean cuttings. Eupatoriochromene has insecticidal activity, it exhibits toxicity againstCulex pipiens (house mosquito) larvae andOncopeltus fasciatus (large milkweed bug) nymphs.
-
Aspartame
阿斯巴甜是一种人造非糖甜味剂，在某些食品和饮料中用作糖替代品。
-
Rhaponticin 6-O-gall...
Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
