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HJC0197
CAS No. 1383539-73-8
HJC0197 ( —— )
产品货号. M22183 CAS No. 1383539-73-8
HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥689 | 有现货 |
|
| 10MG | ￥1053 | 有现货 |
|
| 25MG | ￥1847 | 有现货 |
|
| 50MG | ￥2989 | 有现货 |
|
| 100MG | ￥4447 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称HJC0197
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).
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产品描述HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2). In the presence of an equal concentration of cAMP, HJC0197 (25 μM) also inhibits Epac1-mediated Rap1-GDP exchange activity at 25 μM.
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同义词——
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通路Others
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靶点Other Targets
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受体Epac1;Epac2
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研究领域——
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适应症——
化学信息
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CAS Number1383539-73-8
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分子量339.45
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分子式C19H21N3OS
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纯度>98% (HPLC)
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溶解度——
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SMILESCc1ccc(C)c(CSc2nc(C3CCCC3)c(C#N)c(=O)[nH]2)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chen H, et al. 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.
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