• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

meplazumab

CAS No. ——

meplazumab ( —— )

产品货号. M22102 CAS No. ——

meplazumab 是一种人源化抗 CD147 抗体,作为 COVID-19 肺炎患者的附加疗法。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    meplazumab
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    meplazumab 是一种人源化抗 CD147 抗体,作为 COVID-19 肺炎患者的附加疗法。
  • 产品描述
    meplazumab is a humanized anti-CD147 antibody, as add-on therapy in patients with COVID-19 pneumonia.Compared to control group, meplazumab treatment significantly improved the discharged (p=0.006) and case severity (p=0.021) in critical and severe patients.?The time to virus negative in meplazumab group was reduced than that in control group (median 3, 95%CI[1.5-4.5] vs. 13, [6.5-19.5];?p=0.014, HR=0.37, 95%CI[0.155-0.833]).?The percentages of patients recovered to the normal lymphocyte count and CRP concentration were also increased remarkably and rapidly in meplazumab group.?No adverse effect was found in meplazumab-treated patients.?Interpretation:Meplazumab efficiently improved the recovery of patients with SARS-CoV-2 pneumonia with a favorable safety profile.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    ——
  • 分子量
    ——
  • 分子式
    ——
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Huijie Bian, Zhao-Hui Zheng, Ding Wei,et al.Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial.bioRxiv.2020.
产品手册
关联产品
  • Cinnamtannin A2

    Cinnamtannin A2, a tetrameric procyanidin, enhances GLP-1 and insulin secretion in mice while also upregulating the expression of corticotrophin releasing hormone.

  • N-methyl-1H-indole-2...

    Indole-2-carbaicacidmethylamide 是一种海洋衍生的天然产物,存在于 Neosartoryapseudofischeri 中。

  • 2-Methylglutaric aci...

    2-甲基戊二酸是一种有机酸,通常存在于健康成人和儿童的尿液中。 2-甲基戊二酸是柠檬酸循环中间体琥珀酸的代谢产物。