euphol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Euphol 是一种醇四环三萜烯，具有广泛的药理特性，被认为具有抗炎作用。

Euphol an alcohol tetracyclic triterpene has a wide range of pharmacological properties and is considered to have anti-inflammatory action.

Euphol (0.01-0.3 mM; 24-72 hours) markedly inhibits T47D cells proliferation, the IC50 values of euphol treatment for 24, 48 and 72 h were 0.26, 0.22 and 0.13 mM, respectively.Euphol (0.03 mM; 48 or 72 hours) leads to cell cycle arrest by regulating expression of cell cycle-associated proteins. Cell Proliferation Assay Cell Line:T47D cells Concentration:0.01, 0.03, 0.1 and 0.3 mM Incubation Time:24, 48 and 72 hours Result:Decreased the percentage of viable cells.Western Blot Analysis Cell Line:T47D cells Concentration:0.03 mM Incubation Time:48 and 72 hours Result:Increased the expression of p21 and p27, reduced the expression of cyclin A, B1 and D.

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Others

Other Targets

Others

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514-47-6

426.7

C30H50O

>98% (HPLC)

In Vitro:?DMSO : 25 mg/mL (58.59 mM)

[H][C@]1(CC[C@]2(C)C3=C(CC[C@@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CC\C=C(/C)C

(3S5R10R13R14S17R)-44101314-pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2345671011121314151617-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

(-20℃)

With Ice Pack

≥ 2 years