
erythro-Austrobailignan-6
CAS No. 114127-24-1
erythro-Austrobailignan-6 ( —— )
产品货号. M32474 CAS No. 114127-24-1
erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNA topoisomerase I and II activity. erythro-Austrobailignan-6 induces cell apoptosis and increases phosphorylation of p38 and JNK.
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥4040 | 有现货 |
![]() ![]() |
50MG | 获取报价 | 有现货 |
![]() ![]() |
100MG | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称erythro-Austrobailignan-6
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNA topoisomerase I and II activity. erythro-Austrobailignan-6 induces cell apoptosis and increases phosphorylation of p38 and JNK.
-
产品描述erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNA topoisomerase I and II activity. erythro-Austrobailignan-6 induces cell apoptosis and increases phosphorylation of p38 and JNK .
-
体外实验Cell Viability Assay Cell Line:4T-1 and MCF-7 cells Concentration:0-30 μM Incubation Time:24 or 48 h Result:Dose dependently inhibited cell proliferation.Western Blot Analysis Cell Line:4T-1 and MCF-7 cells Concentration:100 μM Incubation Time:30, 60 or 120 min Result:Increased phosphorylation of p38 and JNK.Activated caspase-3 and inhibited CDK-4 and cyclin D1.
-
体内实验Animal Model:4T-1 tumor bearing mice Dosage:20 mg/kg/day Administration:Food intake Result:Inhibited tumor growth by 40.8%;Down-regulated CDK-4, cyclin D1, HER2 and integrin β3; Up-regulated cleaved caspase-3 in tumor.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number114127-24-1
-
分子量328.4
-
分子式C20H24O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册




关联产品
-
Peroxidase
过氧化物酶来自辣根。过氧化物酶积极参与氧化活性氧、先天免疫、激素生物合成和多种疾病的发病机制。
-
Wnt agonist 1
Wnt 激动剂 1 (BML-284) 是一种有效、选择性且具有细胞渗透性的 Wnt 信号传导激活剂。
-
Lirinidine
(+)-Lirinidine具有抗氧化活性,能显着抑制黑色素瘤细胞的增殖;它还显示出对黑色素生成的有效抑制。