021-51111890
购物车（0）
sales@molnova.cn
c-Kit-IN-1
CAS No. 1225278-16-9
c-Kit-IN-1 ( —— )
产品货号. M17203 CAS No. 1225278-16-9
DCC-2618 是 c-Met 和 c-Kit 的有效抑制剂 (IC50<200 nM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥437 | 有现货 |
|
| 5MG | ￥721 | 有现货 |
|
| 10MG | ￥1191 | 有现货 |
|
| 25MG | ￥2592 | 有现货 |
|
| 50MG | ￥4625 | 有现货 |
|
| 100MG | ￥6634 | 有现货 |
|
| 500MG | ￥13689 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称c-Kit-IN-1
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述DCC-2618 是 c-Met 和 c-Kit 的有效抑制剂 (IC50<200 nM)。
-
产品描述DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).(In Vitro):c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
-
体外实验c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of <2 μM, <10 μM and <10 μM, respectively.
-
体内实验——
-
同义词——
-
通路Endocrinology/Hormones
-
靶点CaMK
-
受体c-Kit| c-Met
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number1225278-16-9
-
分子量489.47
-
分子式C26H21F2N5O3
-
纯度>98% (HPLC)
-
溶解度DMSO : ≥ 100 mg/mL. 204.30 mM
-
SMILESCn1cc(cn1)c1nccc(c1)Oc1c(cc(c(c1)F)NC(=O)C1(CC1)C(=O)Nc1ccccc1)F
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
产品手册
关联产品
-
p-Hydroxy-cinnamic a...
p-Hydroxycinnamic Acid 可抑制血小板活性，对于血栓素 B2 产生和脂多糖诱导的前列腺素 E2 产生的 IC50 分别为 371 μM、126 μM。
-
Elziverine
Elziverine is an orally available small molecule calmodulin antagonist.Elziverine in vitro treatment inhibited Ca-loading-induced acanthocyte formation in SHRSP, WKY, and Wistar rats in a concentration-dependent manner.Elziverine can be used for the treatment of neurological disorders, and may be used for the study of cognitive disorders.
-
KN-93 Phosphate B
KN-93是钙离子/钙调蛋白依赖激酶II（CaMKII）抑制剂，能竞争性阻断钙调蛋白与对应激酶的结合，Ki为370 nM。
