alpha-Naphthoflavone ( —— )

产品货号. M18879 CAS No. 604-59-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

alpha-Naphthoflavone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Alpha-Naphthoflavone 是一种合成类黄酮，是一种有效的芳香酶抑制剂，I50 值为 0.5 μM。
产品描述

Alpha-Naphthoflavone, a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.
体外实验

Cell Proliferation Assay Cell Line:HeLa Concentration:0.01, 1, 10, 100 μM Incubation Time:6 days Result:Decreased cell proliferation in a dose-dependent manner with IC50 value of 36.81 μM.Apoptosis Analysis Cell Line:HeLa Concentration:50 μM Incubation Time:12, 24, 36 h Result:Induced a mild but significant apoptosis rate.Western Blot Analysis Cell Line:HeLa Concentration:50 μM Incubation Time:12, 24, 36 h Result:Increased the level of p53 at 12 h.
体内实验

Animal Model:HFD-induced mice model Dosage:80, 160 mg/kg Administration:i.g.Result:Decreased the levels of AST, TG and TC.
同义词

——
通路

Others
靶点

Other Targets
受体

Aromatase
研究领域

Others-Field
适应症

——

计算器

产品手册

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