alpha-Chaconine ( —— )

产品货号. M31334 CAS No. 20562-03-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

alpha-Chaconine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
产品描述

Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
体外实验

α-Chaconine attenuates the transcriptional activity of activator protein-1 (AP-1) by reducing the translocation and phosphorylation of c-Jun.α-Chaconine suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.α-Chaconine also suppresses the phosphorylation of TGF-β-activated kinase-1 (TAK1), which lies upstream of MKK7/JNK signaling.
体内实验

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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计算器

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