ZPCK ( Z-L-Phe chloromethyl ketone;NSC 251810;SL 01 )

产品货号. M13792 CAS No. 26049-94-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

ZPCK
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ZPCK is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells.
产品描述

ZPCK (NSC 251810;SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells; also modulates autophagic flux in a novel model plant, Aponogeton madagascariensis.
同义词

Z-L-Phe chloromethyl ketone;NSC 251810;SL 01
通路

Autophagy
靶点

Autophagy
受体

Autophagy
研究领域

——
适应症

——

CAS Number

26049-94-5
分子量

331.80
分子式

C18H18ClNO3
纯度

>98% (HPLC)
溶解度

——
SMILES

O=C(OCC1=CC=CC=C1)N[C@H](C(CCl)=O)CC2=CC=CC=C2
化学全称

N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid, phenylmethyl ester

1. Mishra P, et al. Autophagy. 2017 Aug 9:1-17.

计算器

产品手册

关联产品

UNC669

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
Glaucocalyxin B

Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).
Hemin

Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.