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ZK824190
CAS No. 2254001-81-3
ZK824190 ( —— )
产品货号. M26523 CAS No. 2254001-81-3
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥4609 | 有现货 |
|
| 10MG | ￥6610 | 有现货 |
|
| 25MG | ￥10125 | 有现货 |
|
| 50MG | ￥13608 | 有现货 |
|
| 100MG | ￥18387 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ZK824190
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).
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产品描述ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA). The IC50 values are 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.(In Vivo):In rats with experimental autoimmune encephalomyelitis (EAE) model, ZK824190 (2?mg/kg; p.o.) exhibited a relatively high oral availability(F?=?55%; Cmax=?0.64?g/mL and AUC?=?2.2?h*g/mL) and a moderate half time of 2.8 h.
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同义词——
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通路Others
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靶点Other Targets
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受体5-HT3
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研究领域——
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适应症——
化学信息
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CAS Number2254001-81-3
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分子量414.4
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分子式C22H20F2N2O4
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纯度>98% (HPLC)
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溶解度——
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SMILESCC[C@@H](Oc1nc(Oc2cccc(c2)-c2cccc(CN)c2)c(F)cc1F)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kilpatrick GJ, et al. 1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist. Eur J Pharmacol. 1990 Jun 21;182(1):193-7.
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