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ZK824190

CAS No. 2254001-81-3

ZK824190 ( —— )

产品货号. M26523 CAS No. 2254001-81-3

ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥4609 有现货
10MG ¥6610 有现货
25MG ¥10125 有现货
50MG ¥13608 有现货
100MG ¥18387 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ZK824190
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).
  • 产品描述
    ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA). The IC50 values are 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.(In Vivo):In rats with experimental autoimmune encephalomyelitis (EAE) model, ZK824190 (2?mg/kg; p.o.) exhibited a relatively high oral availability(F?=?55%; Cmax=?0.64?g/mL and AUC?=?2.2?h*g/mL) and a moderate half time of 2.8 h.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    5-HT3
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2254001-81-3
  • 分子量
    414.4
  • 分子式
    C22H20F2N2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC[C@@H](Oc1nc(Oc2cccc(c2)-c2cccc(CN)c2)c(F)cc1F)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kilpatrick GJ, et al. 1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist. Eur J Pharmacol. 1990 Jun 21;182(1):193-7.
产品手册
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