Xenalipin
CAS No. 84392-17-6
Xenalipin ( BW 207U )
产品货号. M27180 CAS No. 84392-17-6
谢那利平具有降血脂作用。它可以降低大鼠的血液胆固醇和甘油三酯。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ¥316 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Xenalipin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述谢那利平具有降血脂作用。它可以降低大鼠的血液胆固醇和甘油三酯。
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产品描述Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
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体外实验——
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体内实验4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys. Animal Model:Diet-induced hypercholesterolemic African green monkeys Dosage:15-60 mg/kg Administration:Oral administration (p.o.)Result:Reduced serum LDL-cholesterol concentrations.
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同义词BW 207U
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通路Others
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靶点Other Targets
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受体SIRT1| SIRT2| SIRT3
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研究领域——
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适应症——
化学信息
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CAS Number84392-17-6
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分子量266.219
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分子式C14H9F3O2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : ≥ 250 mg/mL (939.07 mM)
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SMILESOC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.
产品手册
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