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XY101
CAS No. 2349368-16-5
XY101 ( —— )
产品货号. M26510 CAS No. 2349368-16-5
XY101 是一种选择性、代谢稳定、口服的 RORγ 逆激动剂（IC50 为 30 nM，Kd 为 380 nM）。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2341 | 有现货 |
|
| 10MG | ￥4026 | 有现货 |
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| 25MG | ￥6423 | 有现货 |
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| 50MG | ￥9153 | 有现货 |
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| 100MG | ￥12312 | 有现货 |
|
| 500MG | ￥24057 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称XY101
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述XY101 是一种选择性、代谢稳定、口服的 RORγ 逆激动剂（IC50 为 30 nM，Kd 为 380 nM）。
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产品描述XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).(In Vitro):XY101 effectively inhibits cell growth, colony formation and expression of androgen receptor (AR), AR-V7 and prostate specific antigen (PSA).(In Vivo):XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss.
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体外实验XY101 potently inhibits cell growth, colony formation, and the expression of androgen receptor (AR), AR-V7 and prostate-specific antigen (PSA).
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体内实验XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss.
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同义词——
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通路Others
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靶点Other Targets
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受体α-synuclein
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研究领域——
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适应症——
化学信息
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CAS Number2349368-16-5
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分子量563.49
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分子式C25H20F7NO4S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 250 mg/mL (443.67 mM)
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SMILESCCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)-c2ccc(cc2F)C(O)(C(F)(F)F)C(F)(F)F)cc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Pujols J, et al. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486.
