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XRK3F2
CAS No. ——
XRK3F2 ( —— )
产品货号. M16928 CAS No. ——
XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells.
纯度: 99.03% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
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| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称XRK3F2
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells.
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产品描述XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells; inhibits TNFα-induced osteoclast formation, and has IC50 of 4.35 uM 5TGM1 cells and 4.6 uM for the human MM1.S cell line; induces new cortical bone formation in MMBD in vivo, and alters MM cell-BMSC cell interactions by reducing MM cell-derived TNFα in the myeloma microenvironment.
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同义词——
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通路Autophagy
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靶点Autophagy
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受体Autophagy
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量435.90
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分子式C23H24ClF2NO3
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纯度99.03% (HPLC)
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溶解度——
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SMILESCN(CCO)C1=CC=C(OCC2=CC=C(F)C=C2)C(OCC3=CC=C(F)C=C3)=C1.[H]Cl
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化学全称2-((3,4-bis((4-fluorobenzyl)oxy)benzyl)amino)ethan-1-ol hydrochloride
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Teramachi J, et al. Leukemia. 2016 Feb;30(2):390-8.
2.Adamik J, et al. Front Endocrinol (Lausanne). 2018 Jun 29;9:344.
2.Adamik J, et al. Front Endocrinol (Lausanne). 2018 Jun 29;9:344.
产品手册
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