021-51111890
购物车（）
sales@molnova.cn
WR-99210
CAS No. 30711-93-4
WR-99210 ( 6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base) )
产品货号. M24237 CAS No. 30711-93-4
WR-99210 是恶性疟原虫二氢叶酸还原酶 (pfDHFR) 的有效抑制剂，而 pfDHFR 是主要的疟疾药物靶点。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2333 | 有现货 |
|
| 10MG | ￥3345 | 有现货 |
|
| 25MG | ￥5573 | 有现货 |
|
| 50MG | ￥7930 | 有现货 |
|
| 100MG | ￥10692 | 有现货 |
|
| 500MG | ￥21303 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称WR-99210
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述WR-99210 是恶性疟原虫二氢叶酸还原酶 (pfDHFR) 的有效抑制剂，而 pfDHFR 是主要的疟疾药物靶点。
-
产品描述WR-99210 is a potent inhibitor of?Plasmodium falciparum?dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
-
体外实验——
-
体内实验——
-
同义词6,6-Dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,6-dihydro-1,3,5-triazine-2,4-diamine | WR99210 hydrochloride(47326-86-3 free base)
-
通路Others
-
靶点Other Targets
-
受体pfDHFR
-
研究领域——
-
适应症——
化学信息
-
CAS Number30711-93-4
-
分子量431.14
-
分子式C14H19Cl4N5O2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESNC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Canfield C J , Milhous W K , Ager A L , et al. PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.[J]. American Journal of Tropical Medicine & Hygiene, 1993, 49(1):121.
产品手册
关联产品
-
DL-Buthionine-(SR)-s...
D,L-Buthionine-(S,R)-sulfoximine 是一种 γ-谷氨酰半胱氨酸合成酶抑制剂，用于治疗实体瘤。
-
Ac-Phe-NH2
Ac-Phe-NH2 是多聚泛素链延长的非竞争性抑制剂，Ki 值为 8 ± 1.2 mM。
-
Sinapaldehyde
Sinapaldehyde has effects against 65 strains of Candida,Sinapaldehyde inhibits prostaglandin synthetase in a dose-dependent way, it dose-dependently inhibits ethyl phenylpropiolate-induced edema of the rat ear, and can inhibit electrically induced contractions of the guinea pig ileum in a dose-dependent way.
