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WAY-100635 maleate (b)
CAS No. 634908-75-1
WAY-100635 maleate (b) ( WAY 100635 maleate salt | WAY100635 maleate salt )
产品货号. M15399 CAS No. 634908-75-1
WAY-100635 是一种有效的选择性 5-HT1A 受体拮抗剂；也可作为 D4 受体的有效完全激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥308 | 有现货 |
|
| 5MG | ￥494 | 有现货 |
|
| 10MG | ￥778 | 有现货 |
|
| 25MG | ￥1312 | 有现货 |
|
| 50MG | ￥1928 | 有现货 |
|
| 100MG | ￥2851 | 有现货 |
|
| 500MG | ￥6877 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称WAY-100635 maleate (b)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述WAY-100635 是一种有效的选择性 5-HT1A 受体拮抗剂；也可作为 D4 受体的有效完全激动剂。
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产品描述WAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor; completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.Anxiety Phase 1 Discontinued.
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体外实验——
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体内实验——
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同义词WAY 100635 maleate salt | WAY100635 maleate salt
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通路GPCR/G Protein
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靶点5-HT Receptor
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受体5-HT1A
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研究领域Neurological Disease
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适应症Anxiety
化学信息
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CAS Number634908-75-1
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分子量538.6352
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分子式C29H38N4O6
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 34 mg/mL
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SMILESCOC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4.C(=CC(=O)O)C(=O)O
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化学全称Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (9CI)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
产品手册
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