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Vorsetuzumab
CAS No. 1165740-62-4
Vorsetuzumab ( —— )
产品货号. M36867 CAS No. 1165740-62-4
Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) 是抗人 CD70 抗体。Vorsetuzumab 能够增强肾癌细胞巨噬相关吞噬作用，对Burkitt 淋巴瘤具有抑制作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2545 | 有现货 |
|
| 5MG | ￥4813 | 有现货 |
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| 10MG | ￥7744 | 有现货 |
|
| 25MG | ￥11104 | 有现货 |
|
| 50MG | ￥15014 | 有现货 |
|
| 100MG | ￥19814 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Vorsetuzumab
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) 是抗人 CD70 抗体。Vorsetuzumab 能够增强肾癌细胞巨噬相关吞噬作用，对Burkitt 淋巴瘤具有抑制作用。
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产品描述Vorsetuzumab (Anti-Human CD70 Recombinant Antibody) is a human anti-CD70 antibody. Vorsetuzumab enhances macrophage-related phagocytosis of renal carcinoma cells, shows inhibitory efficacy against Burkitt’s lymphoma.
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体外实验Vorsetuzumab (10 μg/mL; 2 h) augments macrophage-dependent phagocytosis of renal carcinoma cells in vitro.Vorsetuzumab (10 μg/mL; 2 h) can be developed into bispecific anti-human CD70/KWAR23 antibody, results KWAR23 moderately induced macrophage phagocytosis of four renal carcinoma cell lines (RCC4, RCC10, TK10, and Caki-1).
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体内实验Vorsetuzumab (10 mg/kg; i.p.; every other day; for 12 d) inhibits Burkitt’s lymphoma cell growth growth in SRG mice.Animal Model:Burkitt’s lymphoma xenograft model in SRG mice Dosage:10 mg/kg Administration: Intraperitoneal injection; every other day; for 12 d Result:Effectively inhibited Burkitt’s lymphoma cell growth but was not outperform the combination of the KWAR23 antibody (10 mg/kg).
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同义词——
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通路Others
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靶点Other Targets
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受体Immunology/Inflammation related
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研究领域——
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适应症——
化学信息
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CAS Number1165740-62-4
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ring NG, et al. Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):E10578-E10585.?
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