Vercirnon

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Vercirnon 是一种选择性且有效的 CCR9 拮抗剂 (IC50: 10 nM)。它还用于炎症性肠病的研究。

Vercirnon is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.

——

Animal Model:C57BL/6 mice (TNFΔARE Mouse Model of Terminal Ileitis)Dosage:10, 50 mg/kg Administration:Subcutaneous; twice per day; starting at 2 weeks of age until 12 weeks of age Result:Resulted in complete protection from the severe inflammation associated with TNF- overexpression at 50 mg/kg. A similar protective effect was also noted with a lower dose.

GSK-1605786 | CCX282-B | Traficet-EN

Others

Other Targets

CCR9

——

——

698394-73-9

444.93

C22H21ClN2O4S

>98% (HPLC)

DMSO : 22.25 mg/mL (50 mM)

CC(C)(C)c(cc1)ccc1S(Nc(ccc(Cl)c1)c1C(c(cc1)cc[n+]1[O-])=O)(=O)=O

——

(-20℃)

With Ice Pack

≥ 2 years