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Valbenazine
CAS No. 1025504-45-3
Valbenazine ( NBI-98854 )
产品货号. M10117 CAS No. 1025504-45-3
一种新型、高选择性囊泡单胺转运蛋白 2 (VMAT2) 抑制剂;被批准用于治疗迟发性运动障碍。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥543 | 有现货 |
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5MG | ¥1094 | 有现货 |
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10MG | ¥1596 | 有现货 |
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25MG | ¥3621 | 有现货 |
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50MG | ¥5241 | 有现货 |
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100MG | ¥7476 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Valbenazine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述一种新型、高选择性囊泡单胺转运蛋白 2 (VMAT2) 抑制剂;被批准用于治疗迟发性运动障碍。
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产品描述A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical(In Vitro):Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively. (In Vivo):Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.
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体外实验——
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体内实验——
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同义词NBI-98854
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number1025504-45-3
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分子量418.5695
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分子式C24H38N2O4
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESCC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC
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化学全称L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. O'Brien CF, et al. Mov Disord. 2015 Oct;30(12):1681-7.