Vagistat ( (±)-Tioconazole )

产品货号. M15506 CAS No. 65899-73-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Vagistat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast.
产品描述

Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability.
同义词

(±)-Tioconazole
通路

Microbiology/Virology
靶点

Antifection
受体

14-α Demethylase
研究领域

Infection
适应症

——

CAS Number

65899-73-2
分子量

387.71
分子式

C16H13Cl3N2OS
纯度

>98%(HPLC)
溶解度

Ethanol: 78 mg/mL (201.18 mM); DMSO: 78 mg/mL (201.18 mM)
SMILES

C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
化学全称

1-(2-((2-chlorothiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

1.Ballard SA, et al. Biochem Pharmacol. 1988 Dec 15;37(24):4643-5

计算器

产品手册

关联产品

Myristicin

Myristicin is a natural product found in spices and umbelliferous plants.?Myristicin has anti-cholinergic, antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway.?
Dendrid

Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.
7-Hydroxyflavanone

7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.