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Vacuolin-1
CAS No. 351986-85-1
Vacuolin-1 ( Vacuolin 1;Vacuolin1 )
产品货号. M14199 CAS No. 351986-85-1
A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥583 | 有现货 |
|
| 10MG | ￥915 | 有现货 |
|
| 25MG | ￥1766 | 有现货 |
|
| 50MG | ￥3208 | 有现货 |
|
| 100MG | ￥4771 | 有现货 |
|
| 500MG | ￥10368 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Vacuolin-1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.
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产品描述A potent PIKfyve inhibitor that inhibits autophagy by impairing lysosomal maturation, potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A; blocks the Ca(2+)-dependent exocytosis of lysosomes induced by ionomycin or plasma membrane wounding, without affecting the process of resealing, induces the formation of giant vacuoles.
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同义词Vacuolin 1;Vacuolin1
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通路Autophagy
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靶点Autophagy
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受体Autophagy
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研究领域——
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适应症——
化学信息
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CAS Number351986-85-1
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分子量577.40
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分子式C26H24IN7O
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纯度>98% (HPLC)
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溶解度——
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SMILESIC1=CC(/C=N/NC2=NC(N(C3=CC=CC=C3)C4=CC=CC=C4)=NC(N5CCOCC5)=N2)=CC=C1
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化学全称(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-morpholino-N,N-diphenyl-1,3,5-triazin-2-amine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Cerny J, et al. EMBO Rep. 2004 Sep;5(9):883-8.
2. Shaik GM, et al. Cell Signal. 2009 Aug;21(8):1337-45.
3. Lu Y, et al. Autophagy. 2014;10(11):1895-905.
4. Sano O, et al. FEBS Lett. 2016 Jun;590(11):1576-85.
2. Shaik GM, et al. Cell Signal. 2009 Aug;21(8):1337-45.
3. Lu Y, et al. Autophagy. 2014;10(11):1895-905.
4. Sano O, et al. FEBS Lett. 2016 Jun;590(11):1576-85.
产品手册
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