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Vaborbactam

CAS No. 1360457-46-0

Vaborbactam ( RPX-7009 )

产品货号. M11479 CAS No. 1360457-46-0

A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2811 有现货
50MG ¥12069 有现货
100MG ¥16119 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Vaborbactam
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains.
  • 产品描述
    A serine β-lactamase inhibitor that notably restores the activity of carbapenems against KPC-producing strains; restores meropenem activity for 72.7 to 98.1% of CPE isolates at ≤2 ug/ml; showes no antibacterial activity alone (MICs, >64 ug/ml).Bacterial Infection Approved
  • 同义词
    RPX-7009
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Infection
  • 适应症
    Bacterial Infection

化学信息

  • CAS Number
    1360457-46-0
  • 分子量
    297.14
  • 分子式
    C12H16BNO5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mM
  • SMILES
    O=C(O)C[C@@H]1CC[C@H](NC(CC2=CC=CS2)=O)B(O)O1
  • 化学全称
    1,2-Oxaborinane-6-acetic acid, 2-hydroxy-3-[[2-(2-thienyl)acetyl]amino]-, (3R,6S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Castanheira M, et al. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5454-8.
2. Hecker SJ, et al. J Med Chem. 2015 May 14;58(9):3682-92.
3. Griffith DC, et al. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6326-32.
产品手册
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