021-51111890
购物车（）
sales@molnova.cn
VUT-MK142
CAS No. 1313491-22-3
VUT-MK142 ( —— )
产品货号. M22884 CAS No. 1313491-22-3
VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥956 | 有现货 |
|
| 5MG | ￥1596 | 有现货 |
|
| 10MG | ￥2406 | 有现货 |
|
| 25MG | ￥4836 | 有现货 |
|
| 50MG | ￥6707 | 有现货 |
|
| 100MG | ￥9315 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称VUT-MK142
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?
-
产品描述VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.VUT-MK142 was identified as the most promising candidate with respect to cardiomyogenic activity.?Treatment using this novel agent induced the strongest up-regulation of expression of the cardiac marker ANF in both P19 embryonic carcinoma cells and C2C12 skeletal myoblasts.?The activity of VUT-MK142 on this marker superseded CgC;?moreover, the novel compound significantly up-regulated the expression of other cardiac markers, and promoted the development of beating cardiomyocytes from cardiovascular progenitor cells.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number1313491-22-3
-
分子量298.4
-
分子式C17H22N4O
-
纯度>98% (HPLC)
-
溶解度DMSO:25 mg/mL (83.79 mM; Need ultrasonic)
-
SMILESCOC1=CC=C(NC2=CC(NC3CCCCC3)=NC=N2)C=C1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Moumita Koley, et al. VUT-MK142 : a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes. Medchemcomm. 2013 Aug 1;4(8):1189-1195.
产品手册
关联产品
-
Penduletin
Penduletin has anti-inflammatory,anti-tumor cells, and anti-bacterical activities,it inhibits growth of the Gram-negative pathogen neisseria gonorrhoeae. Penduletin has strong activity in vitro against EV71 with low cytotoxicity.
-
Hellebrigenin
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
-
Gaboxadol (hydrochlo...
Gaboxadol (hydrochloride) is a GABAA receptor agonist.
