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VPC-13163

CAS No. 6637-10-1

VPC-13163 ( VPC 13163; VPC13163; NSC 52361; NSC52361; NSC52361; 2,3-dihydro-2,3'-Bi-1H-indole )

产品货号. M27934 CAS No. 6637-10-1

VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥2722 有现货
10MG ¥4026 有现货
25MG ¥6423 有现货
50MG ¥9153 有现货
100MG ¥12312 有现货
500MG ¥24057 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    VPC-13163
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.
  • 产品描述
    VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
  • 同义词
    VPC 13163; VPC13163; NSC 52361; NSC52361; NSC52361; 2,3-dihydro-2,3'-Bi-1H-indole
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    CCK
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    6637-10-1
  • 分子量
    234.3
  • 分子式
    C16H14N2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C1C(Nc2ccccc12)c1c[nH]c2ccccc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Eric Lattmann, et al. A preparation of novel ureido - and amido-?pyrazolone derivatives, useful as CCK receptor ligands and CCK antagonists. WO2004106306A1
产品手册
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