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VBY-825
CAS No. 1310340-58-9
VBY-825 ( —— )
产品货号. M26497 CAS No. 1310340-58-9
VBY-825 是一种可逆的组织蛋白酶抑制剂，对组织蛋白酶 B、L、S 和 V 具有高效力。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥3345 | 有现货 |
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| 5MG | ￥5581 | 有现货 |
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| 10MG | ￥7930 | 有现货 |
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| 25MG | ￥11826 | 有现货 |
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| 50MG | ￥15876 | 有现货 |
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| 100MG | ￥21465 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称VBY-825
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述VBY-825 是一种可逆的组织蛋白酶抑制剂，对组织蛋白酶 B、L、S 和 V 具有高效力。
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产品描述VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.(In Vitro):VBY-825 is a potent assayed cathepsins inhibitor and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse.(In Vivo):10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.
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体外实验——
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体内实验——
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同义词——
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通路Proteasome/Ubiquitin
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靶点Cysteine Protease
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1310340-58-9
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分子量535.55
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分子式C23H29F4N3O5S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (233.40 mM)
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SMILESCC[C@H](NC(=O)[C@H](CS(=O)(=O)CC1CC1)N[C@@H](c1ccc(F)cc1)C(F)(F)F)C(=O)C(=O)NC1CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kimura M, Kimura I, Muroi M, Nojima H, Diwan PV. Depolarizing neuromuscular blocking action of coryneine derived from aconite root in isolated mouse phrenic nerve-diaphragm muscles. Biol Pharm Bull. 1995 May;18(5):691-5.
