UUN44923 ( FTO-IN-1 )

产品货号. M24020 CAS No. 2243944-92-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

UUN44923
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

UUN44923 是一种 FTO 抑制剂。它可能有助于治疗相关疾病。 FTO的目标包括肥胖、代谢综合征(MS)、2型糖尿病(T2D)、阿尔茨海默病、乳腺癌、小细胞肺癌、人骨髓横纹肌癌、胰腺癌、恶性胶质母细胞瘤等。
产品描述

UUN44923 is a FTO inhibitor.?It may be useful for treating diseases assocd.?with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like.?
体外实验

FTO-IN-1 (50 μM) inhibits FTO enzyme activity by 62% in vitro.FTO-IN-1 (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively.
体内实验

——
同义词

FTO-IN-1
通路

Others
靶点

Other Targets
受体

FTO
研究领域

——
适应症

——

计算器

产品手册

关联产品

NSC228155

NSC228155 是 EGFR 激活剂，与 sEGFR 二聚化结构域 II 结合并调节 EGFR 酪氨酸磷酸化。
Cubebin

Cubebin showes anti-inflammatory, and anticancer activities. It also shows neuroprotective effects, this could be attributed to its brain AChE inhibition and antioxidant activity.
Isoguvacine hydrochl...

Isoguvacine Hydrochloride 是一种 GABA 受体激动剂。 Isoguvacine Hydrochloride 与大鼠突触皮质膜结合并激活 α1β2γ2S、α2β2γ2S、α3β2γ2S、α5β2γ2S 和 ρ1 亚基 GABAA 受体。