URB602 ( URB602, URB-602, URB 602 )

产品货号. M18820 CAS No. 565460-15-3

COA

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HNMR

HPLC

MSDS

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产品名称

URB602
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.
产品描述

URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 μM for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
同义词

URB602, URB-602, URB 602
通路

Others
靶点

Other Targets
受体

rat brain MGL
研究领域

Cancer
适应症

——

1. Hohmann AG, et al. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23;435(7045):1108-12.

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