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UM-171

CAS No. 1448724-09-1

UM-171 ( UM171 )

产品货号. M11925 CAS No. 1448724-09-1

UM-171 is a potent agonist of human hematopoietic stem cell self-renewal.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    UM-171
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    UM-171 is a potent agonist of human hematopoietic stem cell self-renewal.
  • 产品描述
    UM-171 is a potent agonist of human hematopoietic stem cell self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM; enables a robust ex vivo expansion of human CB cells with functionally validated long-term in vivo repopulating capability.Blood Cancer Phase 2 Clinical
  • 同义词
    UM171
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Cancer
  • 适应症
    Blood cancer

化学信息

  • CAS Number
    1448724-09-1
  • 分子量
    487.94
  • 分子式
    C25H27N9
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    N[C@H]1CC[C@H](NC2=C3C(NC4=C3C=CC(C5=NN(C)N=N5)=C4)=NC(CC6=CC=CC=C6)=N2)CC1
  • 化学全称
    (1r,4r)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Fares I, et al. Science. 2014 Sep 19;345(6203):1509-12.
2. Li X, et al. Stem Cell Res. 2017 May;21:32-39.
3. Zonari E, et al. Stem Cell Reports. 2017 Apr 11;8(4):977-990.
产品手册
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