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UM-171
CAS No. 1448724-09-1
UM-171 ( UM171 )
产品货号. M11925 CAS No. 1448724-09-1
UM-171 is a potent agonist of human hematopoietic stem cell self-renewal.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称UM-171
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述UM-171 is a potent agonist of human hematopoietic stem cell self-renewal.
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产品描述UM-171 is a potent agonist of human hematopoietic stem cell self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM; enables a robust ex vivo expansion of human CB cells with functionally validated long-term in vivo repopulating capability.Blood Cancer Phase 2 Clinical
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同义词UM171
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Cancer
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适应症Blood cancer
化学信息
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CAS Number1448724-09-1
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分子量487.94
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分子式C25H27N9
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纯度>98% (HPLC)
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溶解度——
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SMILESN[C@H]1CC[C@H](NC2=C3C(NC4=C3C=CC(C5=NN(C)N=N5)=C4)=NC(CC6=CC=CC=C6)=N2)CC1
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化学全称(1r,4r)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Fares I, et al. Science. 2014 Sep 19;345(6203):1509-12.
2. Li X, et al. Stem Cell Res. 2017 May;21:32-39.
3. Zonari E, et al. Stem Cell Reports. 2017 Apr 11;8(4):977-990.
2. Li X, et al. Stem Cell Res. 2017 May;21:32-39.
3. Zonari E, et al. Stem Cell Reports. 2017 Apr 11;8(4):977-990.
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