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UK-5099
CAS No. 56396-35-1
UK-5099 ( UK-5099, UK 5099, UK5099 )
产品货号. M17544 CAS No. 56396-35-1
UK 5099 is a specific and potent inhibitor of MPC carrier activity. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥332 | 有现货 |
|
| 5MG | ￥543 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1515 | 有现货 |
|
| 50MG | ￥2746 | 有现货 |
|
| 100MG | ￥4099 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称UK-5099
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述UK 5099 is a specific and potent inhibitor of MPC carrier activity. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM).
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产品描述UK-5099 is a specific and potent mitochondrial pyruvate carrier blocker (MCK blocker). The UK5099 treated cells showed significantly higher proportion of side population (SP) fraction and expressed higher levels of stemness markers Oct3/4 and Nanog. Chemosensitivity examinations revealed that the UK5099 treated cells became more resistant to chemotherapy compared to the non-treated cells. MPC blocker (UK5099) application may be an ideal model for Warburg effect studies
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同义词UK-5099, UK 5099, UK5099
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通路Others
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靶点Other Targets
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受体MPC
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研究领域Cancer
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适应症——
化学信息
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CAS Number56396-35-1
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分子量288.3
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分子式C18H12N2O2
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纯度98%
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溶解度DMSO : ≥ 50 mg/mL. 173.43 mM; H2O : < 0.1 mg/mL
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SMILESOC(=O)C(=Cc1cn(-c2ccccc2)c2ccccc12)C#N
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化学全称2-cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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