Tylosin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

泰乐菌素（Fradizine；Tylocine；Tylosin A）是一种广谱抗生素，针对革兰氏阳性菌和有限范围的革兰氏阴性菌。

Tylosin (Fradizine; Tylocine; Tylosin A) is a broad spectrum antibiotic against Gram-positive organisms and a limited range of Gram-negative organisms.

Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit .Tylosin also prevents growth of Gram-negative strains, with MICs of 64 μg/mL, 32 μg/mL, 512 μg/mL and 1 μg/mL for M. haemolytica 11935, P. multocida 4407, E. coli ATCC 25922 and E. coli AS19rlmAI, respectively.

Tylosin (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals. Animal Model:Balb/C mice (2-3 months old, 20-25 g)Dosage:10 mg/kg, 100 mg/kg, 500 mg/kg Administration:Subcutaneous injection Result:Reduced the elevated TNF-α and IL-1β in LPS (250 μg)-treated mice but increased their IL-10 levels.

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Others

Other Targets

Others

Infection

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1401-69-0

916.1

C46H77NO17

>98% (HPLC)

Soluble in DMSO

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(-20℃)

With Ice Pack

≥ 2 years