
Troxipide
CAS No. 30751-05-4
Troxipide ( BRN0493078 | Troxipide | Troxipida | Troxipidum )
产品货号. M13981 CAS No. 30751-05-4
Troxipide 是一种新型全身性非抗分泌性胃细胞保护剂,具有抗溃疡、抗炎和粘液分泌特性,与胃或十二指肠 pH 值无关。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
100MG | ¥405 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Troxipide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Troxipide 是一种新型全身性非抗分泌性胃细胞保护剂,具有抗溃疡、抗炎和粘液分泌特性,与胃或十二指肠 pH 值无关。
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产品描述Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.(In Vitro):Troxipide exerts inhibitory, therapeutic and preventive effects to specifically those in the stomach by enhancing gastric mucosal blood flow and gastric mucosal defense factors and promoting tissue repair, blood circulation, metabolism and GU repair.(In Vivo):Troxipide (40 mg/kg; iv) significantly alleviates gastric ulcer (GU).Troxipide (40 mg/kg; iv) has a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively.
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体外实验Troxipide exerts inhibitory, therapeutic and preventive effects to specifically those in the stomach by enhancing gastric mucosal blood flow and gastric mucosal defense factors and promoting tissue repair, blood circulation, metabolism and GU repair.
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体内实验Troxipide (40 mg/kg; iv) significantly alleviates gastric ulcer (GU). Troxipide (40 mg/kg; iv) has a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively. Animal Model:Normal control group (NCG) and gastric ulcer group (GUG) rat (5% acetic acid 10 mL/kg/day) Dosage:10, 20, 40, 60 mg/kg Administration:Oral; daily; 2 weeks Result:The levels of these cytokines (IL-17, IL-6, TNF-α, IFN-γ and AP-1) were significantly reduced, suggesting that GU was significantly alleviated.Animal Model:NCG and GUG rat Dosage:40 mg/kg for iv Administration:IV Result:Had a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively.
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同义词BRN0493078 | Troxipide | Troxipida | Troxipidum
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通路Others
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靶点Other Targets
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受体Others
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number30751-05-4
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分子量294.35
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分子式C15H22N2O4
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纯度>98% (HPLC)
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溶解度Ethanol: 3 mg/mL (10.19 mM); DMSO: 18 mg/mL (61.15 mM)
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SMILESO=C(NC1CNCCC1)C2=CC(OC)=C(OC)C(OC)=C2
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化学全称3,4,5-trimethoxy-N-(piperidin-3-yl)benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Kusugami K, et al. Dig Liver Dis, 2000, 32(4), 305-31
产品手册




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