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Troxipide

CAS No. 30751-05-4

Troxipide ( BRN0493078 | Troxipide | Troxipida | Troxipidum )

产品货号. M13981 CAS No. 30751-05-4

Troxipide 是一种新型全身性非抗分泌性胃细胞保护剂,具有抗溃疡、抗炎和粘液分泌特性,与胃或十二指肠 pH 值无关。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG ¥405 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Troxipide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Troxipide 是一种新型全身性非抗分泌性胃细胞保护剂,具有抗溃疡、抗炎和粘液分泌特性,与胃或十二指肠 pH 值无关。
  • 产品描述
    Troxipide is a novel systemic non-antisecretory gastric cytoprotective agent with anti-ulcer, anti-inflammatory and mucus secreting properties irrespective of pH of stomach or duodenum.(In Vitro):Troxipide exerts inhibitory, therapeutic and preventive effects to specifically those in the stomach by enhancing gastric mucosal blood flow and gastric mucosal defense factors and promoting tissue repair, blood circulation, metabolism and GU repair.(In Vivo):Troxipide (40 mg/kg; iv) significantly alleviates gastric ulcer (GU).Troxipide (40 mg/kg; iv) has a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively.
  • 体外实验
    Troxipide exerts inhibitory, therapeutic and preventive effects to specifically those in the stomach by enhancing gastric mucosal blood flow and gastric mucosal defense factors and promoting tissue repair, blood circulation, metabolism and GU repair.
  • 体内实验
    Troxipide (40 mg/kg; iv) significantly alleviates gastric ulcer (GU). Troxipide (40 mg/kg; iv) has a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively. Animal Model:Normal control group (NCG) and gastric ulcer group (GUG) rat (5% acetic acid 10 mL/kg/day) Dosage:10, 20, 40, 60 mg/kg Administration:Oral; daily; 2 weeks Result:The levels of these cytokines (IL-17, IL-6, TNF-α, IFN-γ and AP-1) were significantly reduced, suggesting that GU was significantly alleviated.Animal Model:NCG and GUG rat Dosage:40 mg/kg for iv Administration:IV Result:Had a T1/2 of 210 min and 428.73 min for NCG and GUG rat, respectively.
  • 同义词
    BRN0493078 | Troxipide | Troxipida | Troxipidum
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    30751-05-4
  • 分子量
    294.35
  • 分子式
    C15H22N2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 3 mg/mL (10.19 mM); DMSO: 18 mg/mL (61.15 mM)
  • SMILES
    O=C(NC1CNCCC1)C2=CC(OC)=C(OC)C(OC)=C2
  • 化学全称
    3,4,5-trimethoxy-N-(piperidin-3-yl)benzamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kusugami K, et al. Dig Liver Dis, 2000, 32(4), 305-31
产品手册
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