• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Toyocamycin

CAS No. 606-58-6

Toyocamycin ( Vengicide )

产品货号. M22947 CAS No. 606-58-6

Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥316 有现货
10MG ¥478 有现货
25MG ¥932 有现货
50MG ¥1725 有现货
100MG ¥3013 有现货
500MG ¥7039 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Toyocamycin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM).
  • 产品描述
    Toyocamycin is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.
  • 同义词
    Vengicide
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    XBP1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    606-58-6
  • 分子量
    291.26
  • 分子式
    C12H13N5O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:100 mg/mL (343.34 mM; Need ultrasonic)
  • SMILES
    O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C3=C(C(N)=NC=N3)C(C#N)=C2
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Toyocamycin, et al. Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing. Blood Cancer J. 2012 Jul;2(7):e79.
产品手册
关联产品
  • VU 0357017 hydrochlo...

    VU 0357017 hydrochloride is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).

  • Chelidonine hydrochl...

    Chelidonine hydrochloride?is one of the alkaloids of Chelidonium majus which has broad pharmacological activities.

  • Methyl nomilinate

    Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.