Tirapazamine ( Tirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075 )

产品货号. M18344 CAS No. 27314-97-2

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

Tirapazamine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks.
产品描述

Trapazamine, also known as SR-4233,DNA-damaging drug potentially for the treatment of cervical carcinoma, head and neck cancer. Tirapazamine is activated to its toxic form preferentially in the hypoxic areas of solid tumors. Cells in these regions are resistant to killing by radiotherapy and most anticancer drugs. Thus the combination of tirapazamine with conventional anticancer treatments is particularly effective.
同义词

Tirapazamine; Tirazone; SR 4233; SR-4233; WIN 59075
通路

Others
靶点

Other Targets
受体

Others
研究领域

Cancer
适应症

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1.Cai T Y, Liu X W, Zhu H, et al. Molecular cancer therapeutics, 2013: molcanther. 0490.2013.

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