
Thioacetazone
CAS No. 104-06-3
Thioacetazone ( Diazam | Neotibil | Neustab )
产品货号. M21119 CAS No. 104-06-3
硫代乙酰腙是一种缩氨基硫脲,即硫代乙酰腙治疗肺结核。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥389 | 有现货 |
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5MG | ¥648 | 有现货 |
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10MG | ¥786 | 有现货 |
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25MG | ¥1426 | 有现货 |
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50MG | ¥2122 | 有现货 |
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100MG | ¥3151 | 有现货 |
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200MG | ¥4641 | 有现货 |
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500MG | ¥7152 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Thioacetazone
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述硫代乙酰腙是一种缩氨基硫脲,即硫代乙酰腙治疗肺结核。
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产品描述Thioacetazone is a thiosemicarbazone that?thioacetazone treatment of pulmonary tuberculosis.(In Vitro):Thiacetazone is a prodrug that is activated by the mycobacterial monooxygenase EthA, which is also the activator of two other anti-tuberculosis agents, Ethionamide and Isoxyl.(In Vivo):aminobenzaldehydethiosemicarbazone formed/min/mg cytosolic protein, respectively. The ability to metabolize Thiacetazone is the same in the livers of cat, mouse and human, but lagged significantly in that of rat.
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体外实验Thiacetazone is a prodrug that is activated by the mycobacterial monooxygenase EthA, which is also the activator of two other anti-tuberculosis agents, Ethionamide and Isoxyl.
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体内实验The Km and Vmax values for the N-deacetylation of Thiacetazone are 0.57 mM and 0.123 nmol of p-aminobenzaldehydethiosemicarbazone formed/min/mg cytosolic protein, respectively. The ability to metabolize Thiacetazone is the same in the livers of cat, mouse and human, but lagged significantly in that of rat.
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同义词Diazam | Neotibil | Neustab
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通路Others
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靶点Other Targets
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受体others
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研究领域Infection
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适应症Mycobacterium Avium-intracellulare Infection
化学信息
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CAS Number104-06-3
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分子量236.29
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分子式C10H12N4OS
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (423.21 mM)
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SMILESCC(=O)Nc1ccc(/C=N/NC(N)=S)cc1
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化学全称Acetamide N-(4-(((aminothioxomethyl)hydrazono)methyl)phenyl)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.K.A.-T.A.a.G.T.S.: Hong. A controlled comparison of thiacetazone (thioacetazone) plus isoniazid with pas plus isoniazid in Hong Kong[J]. tubercle 1968 49(3):243-280.
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