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Thalidomide-NH-CH2-COOH

CAS No. 927670-97-1

Thalidomide-NH-CH2-COOH ( (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine; 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid )

产品货号. M28260 CAS No. 927670-97-1

Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥300 有现货
10MG ¥413 有现货
25MG ¥648 有现货
50MG ¥932 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Thalidomide-NH-CH2-COOH
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
  • 产品描述
    Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • 同义词
    (2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine; 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    α7 nAChR
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    927670-97-1
  • 分子量
    331.3
  • 分子式
    C15H13N3O6
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    OC(CNc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Lagostena L, et al. The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus. Neuropharmacology. 2008 Mar;54(4):676-85.
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